Nuclear Therapy
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Nuclear Therapy
Advanced Radionuclide Therapies
Radionuclide therapies are fast gaining importance in the management of several malignancies. Mahatma Gandhi Cancer Hospital & Research Institute is glad to announce the initiation of a Radionuclide Therapy facility for all the patients who are unable to reach places for treatment but can easily find them within a radius of easy reach.
Advantages of Nuclear Therapy:
- Very specific target binding of the pharmaceuticals
- Delivering large doses of radiation to the target tissue
- Very minimal radiation to the normal tissues
- Very minimal side-effect profile
- Significant improvement in quality of life and survival of patients

Following Radionuclide Therapies are available for Cancer Related problems:
- Radioiodine Therapy
- 177 Lu – DOTATATE
- 177 Lu PSMA
- ALPHA Therapy
- 131 Iodine High Dose Therapy
Iodine-131 Therapy is an established modality for management of Thyroid Cancer. It has been used for well differentiated Thyroid Carcinoma both Papillary and Follicular types for
- Remnant Ablation,
- Ablation of Lymphnodal or Local Residual Disease
- Adjuvant treatment of Distant Metastases
- Metastatic Carcinoid and Neuroendocrine Tumors
- Metastatic Pheochromocytoma and Paraganglioma
- Metastatic Neuroblastoma
- Inoperable Meningiomas
177 Lutetium DOTATATE Therapy:
177Lu – DOTATATE Therapy significantly improves outcomes in patients with Progressive Metastatic Neuroendocrine tumors. This therapy can be used in

177 Lutetium PSMA Therapy:
Prostate Specific Membrane Antigen (PSMA) is a Type || Transmembrane Protein expressed on cell surface and normally found in prostate gland, jejunum, salivary glands and kidneys. It is over expressed in Adeno Carcinoma of the Prostate. Targeted Therapy with 177 Lu PSMA is effective in controlling Metastatic Hormone Resistant Prostate Carcinoma.

Treatment of Benign Diseases:
Grave’s Disease / Autonomous Functioning Thyroid Nodule:
- 131-Iodine is a very effective treatment for Grave’s disease and AFTN and reducing size of Multi Nodular Goiter prior to surgery
Radiosynovectomy for Inflammatory Joint Diseases:
- Injection of Radionulides into the joints results in slowing down of disease progression and drastic improvement of pain in patients with Inflammatory Arthritis and is indicated in
- Refractory Painful Inflammatory Arthritis such as Rheumatoid Arthritis and other Spondyloarthritidis
- Hemophilic Arthritis
- Pigmented Villinodular Synovitis
- Persistent Effusion after Joint Prosthesis
- Undifferentiated Arthritis (where the Arthritis is characterized by Synovitis, Synovial Thickening or Effusion)

Center of Excellence in Nuclear Medicine

PET-CT
- FDG PET CT Scan
- PSMA PET-CT for Prostate Cancer
- Ga-DOTANOC Scan for Neuro Endocrine tumors
- Metabolic Imaging for Epilepsy, Dementia, Parkinsonism
- Cardiac PET-CT for Viability & Inflammation
- Metabolic Biopsy
THERAPY
- lodine High dose lodine Therapy for Thyroid Cancer
- 177 Lu DOTATATE Therapy for Neuro Endocrine Tumor
- 177 Lu PSMA Therapy for Prostate Cancer
- Radiation Synovectomy
- Low Dose Radioiodine Therapy for Graves & Disease, Toxic Multinodular Goiter
- Alpha Therapy for Neuroendocrine Tumor and Prostate Cancer