What is Bone Marrow Transplant
Bone Marrow Transplant procedure is performed not only for cancerous conditions like blood cancer but also for a genetic condition like Thalassemia. Here, the cancerous or genetically abnormal stem cells are eradicated by chemotherapy and immuno-suppressive medicines, and new functionally normal stem cells are given, which later populate the bone marrow and blood with normal, non-cancerous, and genetically normal cells.
For the FIRST time in the state of Andhra Pradesh, Mahatma Gandhi Cancer Hospital & Research Institute
Visakhapatnam, which has been in health care service for more than 17 years, is the largest comprehensive, exclusive cancer specialty hospital in Andhra Pradesh, with the largest team of qualified cancer super specialists under one roof, drawn from all premium institutes in India. We are equipped with cutting-edge technology for patient-centric oncology care with evidence-based medicine practices ranging from prevention, early detection, cancer-treatment, and terminal care.
The stem cells in one’s healthy bone marrow are responsible for producing blood cells, especially leukocytes or white blood cells (WBCs) that are essential for the immune system. Blood cancers and their associated treatments, such as chemotherapy and radiation treatments, deplete your bone marrow. Stem cell transplants help in regenerating new cells from the old cells to help your body create more cancer-free cells. The stem cells can be collected either from your own bloodstream or from that of a donor.
Here’s how the transplant process looks
Before the transplant
During the transplant
After the transplant
Mahatma Gandhi Cancer Hospital & Research Institute has launched its state-of-the-art Bone Marrow Transplant (BMT) facility at HealthCity, Arilova, Visakhapatnam, which is the first such exclusive BMT unit in Andhra Pradesh. The unit has four transplant cubicles for transplant patients’ use before and after the procedure. All cubicles are of class-10000 clean room standard and equipped with HEPA filtration systems and positive pressure ventilation. The transplant program team provides a specialized service under the Hemato Oncology department. The team is committed to providing quality service to all children and adults needing this procedure.
About Bone Marrow
Other sources of stem cells have gained popularity in the last decade, because their harvesting is better tolerated by the donor and delivers almost identical success rates when compared to Bone Marrow Transplant. These include Peripheral Blood Stem Cells and Cord Blood Stem Cells.
Some Conditions which require Bone Marrow Transplant ( BMT)
The procedure of Stem Cell Transplant
Before a stem cell transplant, stem cells are collected from either the bone marrow or the blood. The patient is given high doses of chemotherapy, usually over a few days. Sometimes, radiotherapy is also given to the whole body, known as total body irradiation (TBI). This process is known as “conditioning”.
As well as destroying any remaining cancer cells, the high doses of chemotherapy also destroy the stem cells in the bone marrow. After the chemotherapy, the patient is given the stem cells that were collected before the treatment. These stem cells start producing mature blood cells again.
There are Two main types
Steps involved in Bone Marrow Transplant
Risks of Bone Marrow Transplant (BMT)
There are two types of GvHD
Chronic GvHD – Develops after 3 months and can cause symptoms for many years.